Our Platform | Amyloid Plaques 2016-11-18T18:55:02+00:00

Our Platform

amyloid plaque

At Alzheon, we have built an innovative drug development platform that allows us to identify and assess drug candidates based on their ability to target beta amyloid and disrupt disease pathogenesis to improve the memory and cognitive deficits of Alzheimer’s disease as well as other brain disorders. We have developed a thorough understanding of the beta amyloid aggregation process and the mechanism of action of the small molecule drug candidates we design to intervene in the formation of plaques before they impart deleterious effects.

Applying a precision medicine approach, we have combined deep experience in neurology drug development, as well as insights into beta amyloid biology, to establish a proprietary platform for the discovery and advancement of beta amyloid-targeted small molecules.  Our platform includes:

  • An established and growing library of proprietary beta amyloid-targeted small molecules
  • Fundamental knowledge of the amyloid aggregation process to identify compounds that specifically bind and block the critical steps in aggregation of amyloid
  • State-of-the-art clinical development approaches to improve the likelihood of success, including clinical studies designed with insights into patient subpopulations, clinical endpoints, and biomarkers