Scientific Publications
14Jun, 2021
Neurotoxic Soluble Amyloid Oligomers Drive Alzheimer’s Pathogenesis and Represent a Clinically Validated Target for Slowing Disease Progression
Martin Tolar, John Hey, Aidan Power, Susan Abushakra
4Dec, 2020
APOE ε4/ε4 homozygotes with early Alzheimer’s disease show accelerated hippocampal atrophy and cortical thinning that correlates with cognitive decline
Susan Abushakra, Anton P. Porsteinsson, Marwan Sabbagh, Luc Bracoud, Joel Schaerer, Aidan Power, [...]
17Aug, 2020
Aducanumab, gantenerumab, BAN2401, and ALZ-801—the first wave of amyloid targeting drugs for Alzheimer’s disease with potential for near term approval
Martin Tolar, Susan Abushakra, John A. Hey, Anton Porsteinsson and Marwan Sabbagh Abstract [...]
2Dec, 2019
APOE4/4 Subjects with Early Alzheimer’s Disease Show Accelerated Loss of Cortical Thickness and Cognitive Decline Compared to APOE3/3 Subjects
Background & Objectives The apolipoprotein ε4 allele (APOE4) is a major genetic risk [...]
6Nov, 2019
New Alzheon Publication Points to a More Positive Future for Alzheimer’s Drug Development
Targeting ‘Bad’ Forms of Amyloid Validated by Recent Biogen Announcement Click here to [...]
24Oct, 2018
Discovery of an Endogenous Metabolite of Tramiprosate and its Prodrug ALZ-801 that Inhibits Beta Amyloid Oligomer Formation In Human Brain
John A. Hey, Petr Kocis, Jakub Hort, Susan Abushakra, Aidan Power, Martin Vyhnálek, [...]